ASSESSING BREACHES OF BIOCHEMICAL INDICATORS OF THE STATE OF BONE TISSUE IN CHILDREN UNDER CONDITIONS THE AIRBORNE IMPACT PRIORITY OF CHEMICAL FACTORS IN THE ZONE OF INFLUENCE COMPANIES PRODUCING ALUMINUM

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Published: Oct 29, 2018
Keywords:
aluminum air child population biochemical indicators bone oxidant and antioxi-dant processes biological media cause and effect relationships

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Инга/Inga Геннадьевна/Gennadievna Жданова-Заплесвичко/Zhdanova-Zapslevichko
Administration of Rospotrebnadzor in Irkutsk region
Марина/Marina Александровна/Alexandrovna Землянова/Zemlyanova
FBSI «Federal Scientific Center for Medical and Preventive Health»; Perm State University; Perm National Research Polytechnic University
Екатерина/Ekaterina Владимировна/Vladimirovna Пескова/Peskova
FBSI «Federal Scientific Center for Medical and Preventive Health»; Perm State University

Abstract

According to the results of the research, it was found that children living in the zone of aerogenic aluminum exposure at a level of up to 0.00085 mg/(kg-day) showed an excess of aluminum in the bio-environments (in urine, 4.5 times higher than in children Group of comparison and 5.6 times higher than the reference level, in the blood - 1.3 times higher than in the children of the comparison group and 3 times higher than the reference level). A comparative analysis of the laboratory parameters studied revealed abnormalities that characterize the disturbance of the bone tissue state (increase in the level of ionized calcium in the blood, tartrate-resistant acid phosphatase, decrease in phosphorus and N-osteocalcin level in the blood serum), oxidative and antioxidant processes 8-hydroxy-2-deoxyguanosine in the urine, a decrease in the level of AOA in the blood plasma). The relationship between the studied biochemical indicators of negative effects and the concentration of aluminum in the biomeds (blood, urine) of the children examined was proved.

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How to Cite
Жданова-Заплесвичко/Zhdanova-Zapslevichko И. Г., Землянова/Zemlyanova М. А., & Пескова/Peskova Е. В. (2018). ASSESSING BREACHES OF BIOCHEMICAL INDICATORS OF THE STATE OF BONE TISSUE IN CHILDREN UNDER CONDITIONS THE AIRBORNE IMPACT PRIORITY OF CHEMICAL FACTORS IN THE ZONE OF INFLUENCE COMPANIES PRODUCING ALUMINUM. Bulletin of Perm University. Biology, (2), 216–221. Retrieved from https://press.psu.ru/index.php/bio/article/view/1857
Issue
No. 2 (2017): Вестник Пермского университета. Серия «Биология»=Bulletin of Perm University. Biology
Section
Клиническая лабораторная диагностика

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Author Biographies

Инга/Inga Геннадьевна/Gennadievna Жданова-Заплесвичко/Zhdanova-Zapslevichko, Administration of Rospotrebnadzor in Irkutsk region

Candidate of medical sciences, head of the Department of social and hygienic monitoring

Марина/Marina Александровна/Alexandrovna Землянова/Zemlyanova, FBSI «Federal Scientific Center for Medical and Preventive Health»; Perm State University; Perm National Research Polytechnic University

Doctor of medical science, professor, head of the Department of biochemical and cytogenetic diagnostic methods;Professor of the Department of human ecology and life safety;Professor of the Department of environmental protection

Екатерина/Ekaterina Владимировна/Vladimirovna Пескова/Peskova, FBSI «Federal Scientific Center for Medical and Preventive Health»; Perm State University

Master, research assistant laboratory of biochemical and nanosensory methods of diagnostics;Master student of Biological faculty

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