Pathogenic potential of Bacillus cereus sensu stricto and Bacillus thuringiensis
DOI:
https://doi.org/10.17072/1994-9952-2026-2-150-158Keywords:
B. cereus, B. thuringiensis, plasmidsAbstract
Bacillus cereus sensu stricto and Bacillus thuringiensis are genetically the most closely related species to Bacillus anthracis, although they are considered to have a lower pathogenic potential. Furthermore, B. thuringiensis is generally considered safe for humans and mammals and is exclusively used as an entomopathogen. However, a growing body of evidence suggests that the reality is much more complex. This review provides specific examples demonstrating the pathogenic potential of these species, due to the detection of strains harboring genes characteristic of Bacillus anthracis. Particular attention is paid to B. cereus s.s. strains with pXO1- and pXO2-like plasmids, since their presence complicates pathogen identification using existing laboratory methods. Furthermore, since the turn of the millennium, these strains have caused fulminant pneumonia. Cases of toxicoinfection and bacteremia caused by B. thuringiensis strains are also presented. Their potential to cause wound infections in humans is demonstrated. All of this points to an increase in the pathogenic potential of B. cereus s.s. and B. thuringiensis, which requires a revision of the current pathogen control paradigm.References
Список источников
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